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Tadao Serikawa Selected Research

aspartoacylase

1/2009Myelin lipid abnormalities in the aspartoacylase-deficient tremor rat.
4/2007Absence-like and tonic seizures in aspartoacylase/attractin double-mutant mice.
5/2005Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.
7/2004Adenoviral gene transfer of aspartoacylase ameliorates tonic convulsions of spontaneously epileptic rats.
9/2003Activation by N-acetyl-L-aspartate of acutely dissociated hippocampal neurons in rats via metabotropic glutamate receptors.
8/2002Adenoviral gene transfer of aspartoacylase into the tremor rat, a genetic model of epilepsy, as a trial of gene therapy for inherited epileptic disorder.

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Tadao Serikawa Research Topics

Disease

26Seizures (Absence Seizure)
01/2019 - 09/2002
10Tremor (Tremors)
12/2017 - 04/2002
8Epilepsy (Aura)
11/2020 - 08/2002
4Neoplasms (Cancer)
04/2013 - 11/2009
3Glioma (Gliomas)
02/2019 - 08/2012
3Autosomal Dominant Lateral Temporal Lobe Epilepsy
02/2019 - 08/2012
3Carcinogenesis
10/2012 - 04/2008
3Glomerulonephritis
02/2012 - 12/2005
3Canavan Disease (Leukodystrophy, Spongiform)
01/2009 - 05/2002
2Temporal Lobe Epilepsy
01/2018 - 01/2015
2Type 1 Episodic Ataxia
01/2015 - 01/2012
2Inflammation (Inflammations)
07/2014 - 04/2013
2Drug Resistant Epilepsy
01/2013 - 11/2011
2Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
09/2012 - 01/2010
2Myoclonic Epilepsies (Myoclonic Encephalopathy)
05/2011 - 02/2011
2Generalized Epilepsy with Febrile Seizures Plus
05/2011 - 02/2011
2Febrile Seizures (Febrile Seizure)
02/2011 - 04/2010
2IGA Glomerulonephritis (IGA Nephropathy)
12/2005 - 08/2004
1Down Syndrome (Down's Syndrome)
11/2020
1Cognitive Dysfunction
01/2019
1Focal Cortical Dysplasia
01/2018
1Movement Disorders (Movement Disorder)
11/2016
1Insulin Resistance
10/2016
1Dermatitis
11/2015
1Pruritus (Itching)
11/2015
1Atopic Dermatitis (Atopic Eczema)
11/2015
1Type 2 Episodic Ataxia
01/2015
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2014
1Fatty Liver
09/2013
1Cardiovascular Diseases (Cardiovascular Disease)
08/2013
1Colitis
04/2013
1Colorectal Neoplasms (Colorectal Cancer)
10/2012
1Adenocarcinoma
10/2012
1Body Weight (Weight, Body)
10/2012
1Ovarian Neoplasms (Ovarian Cancer)
09/2012
1Limbic Encephalitis (Paraneoplastic Limbic Encephalitis)
08/2012
1Autoimmune Diseases (Autoimmune Disease)
02/2012
1Hyperlipidemias (Hyperlipidemia)
02/2012
1Hypercholesterolemia
02/2012
1Nephritis
02/2012
1Atherosclerosis
02/2012
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
02/2012
1Genetic Predisposition to Disease (Genetic Predisposition)
02/2012

Drug/Important Bio-Agent (IBA)

8Levetiracetam (Keppra)FDA LinkGeneric
01/2018 - 08/2005
8Anticonvulsants (Antiepileptic Drugs)IBA
01/2018 - 07/2004
6Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2009
6aspartoacylaseIBA
01/2009 - 08/2002
5Pentylenetetrazole (Metrazol)IBA
01/2019 - 09/2010
5Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA
12/2017 - 01/2012
4Pharmaceutical PreparationsIBA
08/2012 - 07/2004
3Leucine (L-Leucine)FDA Link
02/2019 - 08/2012
3Ethosuximide (Zarontin)FDA LinkGeneric
08/2012 - 02/2007
3Phenytoin (Dilantin)FDA LinkGeneric
08/2012 - 02/2007
3N-acetylaspartate (N-acetyl aspartate)IBA
05/2005 - 08/2002
2MecamylamineIBA
01/2017 - 11/2016
2methyllycaconitineIBA
01/2017 - 11/2016
2NicotineFDA Link
01/2017 - 11/2016
2sodium sulfate (sodium bisulfate)FDA LinkGeneric
04/2013 - 11/2009
2Dextrans (Dextran)FDA Link
04/2013 - 11/2009
2AntigensIBA
08/2012 - 02/2012
2LipidsIBA
02/2012 - 01/2009
2Valproic Acid (Depakote)FDA LinkGeneric
02/2011 - 02/2007
2CholesterolIBA
04/2008 - 02/2006
2Immunoglobulin A (IgA)IBA
12/2005 - 08/2004
1Amino AcidsFDA Link
11/2020
1NucleotidesIBA
11/2020
1Cell Adhesion MoleculesIBA
11/2020
1gamma-Aminobutyric Acid (GABA)IBA
11/2020
1PotassiumIBA
02/2019
1Pilocarpine (Ocusert)FDA LinkGeneric
01/2019
1Hexamethonium (Hexamethonium Bromide)IBA
11/2016
1Acetylcholine (Acetylcholine Chloride)FDA Link
11/2016
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
11/2016
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2016
1Glucose (Dextrose)FDA LinkGeneric
10/2016
1Immunoglobulin E (IgE)IBA
11/2015
1Ointments (Pastes)IBA
11/2015
1Betamethasone (Celestone)FDA Link
11/2015
1ICI D2788IBA
01/2015
1Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
01/2015
1Messenger RNA (mRNA)IBA
07/2014
1CytokinesIBA
07/2014
1LeptinIBA
09/2013
1CationsIBA
08/2013
1AngiotensinsIBA
08/2013
1Fluorouracil (Carac)FDA LinkGeneric
10/2012
1Calcibiotic Root Canal SealerIBA
10/2012
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
09/2012
1DNA (Deoxyribonucleic Acid)IBA
09/2012
1Carbamazepine (Tegretol)FDA LinkGeneric
08/2012
1LigandsIBA
02/2012
1Fc Receptors (Fc Receptor)IBA
02/2012
1LDL Receptors (LDL Receptor)IBA
02/2012
1AntibodiesIBA
02/2012

Therapy/Procedure

2Therapeutics
05/2011 - 07/2010
2Induced Hyperthermia (Thermotherapy)
05/2011 - 04/2010
1Subcutaneous Injections
10/2012
1Tissue Transplantation
09/2012
1Heterologous Transplantation (Xenotransplantation)
09/2012
1Stem Cell Transplantation
09/2012